Imaging Cell-Mediated Immunity Assesses Acute Myocarditis

Imaging Granzyme B Activity Assesses Immune-Mediated Myocarditis.

RATIONALE The development of molecular imaging approaches that assess specific immunopathologic mechanisms can advance the study of myocarditis. OBJECTIVE This study validates a novel molecular imaging tool that enables the in vivo visualization of granzyme B activity, a major effector of cytotoxic CD8+ T lymphocytes. METHODS AND RESULTS We synthesized and optimized a fluorogenic substrate ...

EVALUATION OF CELL-MEDIATED IMMUNITY IN MUSTARD GAS INJURIES

Yamakido, et al. in 1986 have studied immunological parameters in poison gas workers, and a depression has been observed in immunologic response. Also, the frequency of cancer has reached as high as five-fold that of the general population. In the present study, cell-mediated immunity (CMI) was measured in three groups of Iranian mustard gas-injured patients. The first group were those wh...

Humoral Immunity and Cell-Mediated Immunity

Humoral Immunity and Cell-Mediated Immunity

EVA LUATION OF THE ROLE OF CELL-MEDIATED IMMUNITY IN DERMATOPHYTOSIS

For demonstration of cell-mediated immunity and its role in the process of dermatophytosis, 98 patients with acute dermatophytosis (group I) and 131 chronic dermatophytosis patients (group 2) were chosen. In ail patients, lymphocyte transfonnation and skin test were used. 96 members of group I (98%) had positive delayed-type hypersensitivity (DTH) responses to trichophytin, whereas only 43 ...